The Science of Excellence: Superior Absorption and Safety

CREABEV™

soluble & stable creatine monohydrate for superior performance beverages. the most stable form of creatine monohydrate

Stable at High Processing Temps
Improved Short Term Stability
Improved Dispersion

Features a patent pending encapsulation technology that facilitates a more stable creatine monohydrate.
Contains 68-74% of creatine monohydrate.

suitable for:

1

Acidic and Neutral pH Ready-to-Drink Beverages Extended stability at high processing temperatures
2

Ready-to-Mix Powdered Beverages Improved short term stability and dispersion

what is creatine and what does it do?

What is creatine and
what does it do?

Creatine occurs naturally in the body and is commonly sold as creatine monohydrate as a dietary supplement.
Creatine is the body’s first choice of energy for anaerobic activity.
Studies have consistently indicated that creatine supplementation increases muscle creatine and phosphocreatine concentrations by approximately 15–40% which is used to supply energy to muscles.

The benefits of
Creatine

Increase cellular energy supplies
Enhances anaerobic exercise capacity
Increases training volume
Greater gains in strength, power, and muscle mass

drawbacks of standard creatine monohydrate

Unstable in solution

Standard sources of creatine have poor solubility and are not stable in water due to the degradation to Creatinine ¹

Degrades at room temperature

The rapid degradation of creatine in solution impedes the manufacture of shelf-stable beverages containing efficacious amounts of creatine2

CREABEV™ offers a creatine solution that is stable and soluble in water beverages with less degradation

Creatine is readily degraded to creatinine when stored at room temperature
Creatinine is the waste product derived from creatine and provides no benefits to the body
Creatinine is removed from the body as waste

drawbacks of Standard Creatine Monohydrate

Creabev™ is the ideal solution for your sports nutrition and energy beverage needs

1

Soluble source of creatine for ready-to-drink acidic and neutral pH beveragesHeat stable during heat processing with no crystallization
2

Improved dispersion for ready-to-mix powdered beverages Highly stable creatine in water at room temperature in water

short term acceleration studies

Creabev™’s Superior Short Term Stability

CREABEV™ VS. STANDARD CREATINE MONOHYDRATE

the results are clear:

CREABEV™ After 2 hours, 98.37% of creatine monohydrate from CreaBev™ was present in water
Standard Creatine Monohydrate During the first 5 minutes, 11% of creatine monohydrate was degraded with only 89% remaining

CREABEV™ versus standard creatine
monohydrate in ready-to-mix powdered
beverages

CREABEV™ is more dispersible than standard creatine monohydrate

long term shelf life studies ready-to-drink beverages

12 month stability study of CREABEV™ and standard creatine monohydrate at a neutral PH

the results are clear:

CREABEV™ 70% of creatine monohydrate in CreaBev™ remained stable with only 30% degradation to creatinine
Standard Creatine Monohydrate Within 3 months, 95% of creatine monohydrate had completely degraded. By 12 months there was 100% degradation in creatine monohydrate

12 month stability study of creabev™ in water with bcaas & electrolytes at an acidic ph (2.8)

the results are clear:

CREABEV™ 30% of creatine monohydrate in CreaBev™ remained stable at pH 2.8 after 1 year
Standard Creatine Monohydrate 100% degradation of creatine monohydrate at day 50

CREABEV™ is stable at high processing temperatures

pre-clinical studies bioavailability

CREABEV™ shows positive
results for bioavailability

preclinical rat studies

Creatine Monohydrate from CREABEV™ and Standard Creatine Monohydrate Show Similar Levels within Blood
- CREABEV™ shows similar plasma creatine monohydrate levels as standard creatine monohydrate (30mg/kg CreaBev vs 30mg/kg creatine monohydrate)
- There is no significant difference between the ingredients
CREABEV™ Shows High BioavailabilityCREABEV™ contains 32% less creatine monohydrate than standard creatine monohydrate but shows similar plasma levels making it highly bioavailable

sensory study

CREABEV™ sensory study design

brigham young university (byu) sensory study. prof. laura jeffries
department of nutrition, dietetics, and food science

A sensory panel of 108 participants
evaluated three samples of CREATINE
SPORTS DRINK

CREABEV™
Creatine monohydrate
Creatine HCL

Participants were asked to rate the
following:

Attitude
Appearance
Aroma
Overall acceptability
Flavor
Mouth-feel
Aftertaste
Purchase likelihood
Preference

Ingredients:

Creatine Monohydrate
Cholesterol
Sodium
Caffeine
Protein
Carbohydrates
Sugars
Dietary Fiber
Cluster Dextrin™

CREABEV™ shows similar sensory results
as compared to creatine monohydrate and
better than creatine HCL

CREABEV™ was accepted overall by panelists, preferred over Creatine HCL and was rated more likely to be purchased.
CREABEV™ and creatine monohydrate had similar results for purchase likelihood, preference ranking, flavor, mouthfeel, aftertaste, and expectation acceptability while it performed significantly better than Creatine HCL.
Overall CREABEV™ and Creatine monohydrate received similar ratings for sensory and performed better than Creatine HCL with the exception of aroma acceptability.

study summary

Creabev™ has a good taste profile and acceptability rating with a high level of customer purchasing likelihood.
Encapsulation Technology allowing for increased stability and solubility has no negative impact on sensory for CREABEV™
Creabev™has similar sensory profile to Creatine Monohydrate yet provides additional functional benefits.

Dosage and fortification guide

Regulatory
and data updates

Regulatory:
- Self-Affirmed GRAS – Approved in November 2020 for various food-beverage applications
Clinical data – Coming Soon
- Coming in Q1 2021 – A Human Clinical study assessing the effects of СREABEV™ on digestion and cognitive function.
- Additionally, a Pharmacokinetic study (Bioavailability) in human subjects will be determined

Material specifications

#1088204 CREABEV 20 KG–P (Neutral)

Active Concentration
68% Creatine monohydrate

Physical characteristics
Creamish yellow powder

Suggested Labeling
Creatine monohydrate, maltodextrin, soy lecithin, ɑ-cyclodextrin

Suggested Pricing
$24/kg to $29/kg FOB Caine warehouse in Wisconsin

Availability and Lead Time
Stocked at Caine, WI in USA. Lead time of 10-12 weeks for EMEA based customers

Pack Size:
20kg kraft-bag in a box

#1098430 CREABEV-A 20 KG–P (Acidic)

Active Concentration
74% Creatine monohydrate

Physical characteristics
Creamish yellow powder

Suggested Labeling
Creatine monohydrate, pea fiber, sunflower lecithin

Suggested Pricing
$24/kg to $29/kg FOB Caine warehouse in Wisconsin

Availability and Lead Time
Stocked at Caine, WI in USA. Lead time of 10-12 weeks for EMEA based customers

Pack Size:
20kg kraft-bag in a box

Regulatory

Self-GRAS, GMO Free, Kosher, Halal, EU compliant, Patented, Global trademark

creabev™ market insights

The market for CREABEV™

CREABEV™ is positioned nicely between the growing non protein product and creatine product markets.

$0.7B

Sports Nutrition Non Protein Products In The US Market¹

(ready-to-mix powders)

$100M

Creatine Product Market²

(sports nutrition ready-to-mix powders and ready-to-drink beverages)

Euromonitor International Sports Nutrition in the U.S. December 2015
SPINS Total US – Creatine Products – Convenience, MULO, Natural Channel, Specialty Gourmet Channel and Vitamin Shoppe, December 2017

Consumers Are
Talking About Creatine

2,973

Creatine mentions made by consumers¹

86%

Positive sentiment from consumers on the use of creatine in products¹

Glanbia Nutritionals, Social Listening Report, Jan-March 2018

We know the Creatine Consumer

61%

of Creatine users report using it sometimes, while 39% claim they use it regularly opening up the opportunity to discuss the benefits of regular use

All Natural and US Sourcing are among the most important product claims

60%

of Creatine users workout more than 7 hours per week

Consumers that currently use Creatine tend to use other supplements as well which could be a strong cross-selling opportunity

“I love sports and enjoy going out with my friends to sporting events.”

consumers are familiar with creatine
to enhance workouts

Awareness and usage do not go
hand-in-hand

Creatine users workout preferences

Creatine users are more likely to workout more during the week than the general population
Creatine users are more likely to dedicate their workouts to sports activities such as football, basketball, baseball, hockey, and/or soccer, martial arts, and long distance/endurance sports.
Creatine users are much more likely to dedicate time to weightlifting and competitive body building

Generally, Creatine users are more likely to participate in all workout related activities versus non users

Opportunity lies in discussing
benefits of more regular use

General Population – Creatine Awareness

Of the Creatine users, less than half are regular users

Most creatine users prefer to get their pre
and post workout products via powdered
beverage mixes

Consumers that currently use creatine tend
to use other supplements as well

Product claims are more important to the
creatine user than the general consumer

Creatine users trend higher than the
general consumer in how they evaluate and
respond to products

disclaimer notice

Statements relating to the Products / Services described in this document have not been evaluated by the US Food and Drug Administration.

Claims made relating to the Products / Services described in this document are examples of potential structure/function claims. As with all product claims, use of these claims should be reviewed by your legal/regulatory advisors to make sure that they comply with current regulations.

Creatine.com makes no representations, warranties or guarantees as to, and assumes no responsibility for, the use of the Products / Services described in this document and expressly disclaims all liability for damages of any kind arising out of the use or performance of, reference to, or reliance on Products / Services or any statements made in connection therewith. Specifically, the Products / Services described in this document are not intended to diagnose, treat, cure, or prevent any disease.

The information in this presentation is confidential. No part of this presentation may be modified, printed, or presented without the prior written permission of Creatine.com

CREABEV™

Unstable in solution

Degrades at room temperature

Creabev™’s Superior Short Term Stability

CREABEV™ versus standard creatine monohydrate in ready-to-mix powdered beverages

12 month stability study of CREABEV™ and standard creatine monohydrate at a neutral PH

CREABEV™ shows positive results for bioavailability

CREABEV™ sensory study design

CREABEV™ shows similar sensory results as compared to creatine monohydrate and better than creatine HCL

Dosage and fortification guide

Material specifications

#1088204 CREABEV 20 KG–P (Neutral)

#1098430 CREABEV-A 20 KG–P (Acidic)

Regulatory

The market for CREABEV™

$0.7B

$100M

Consumers Are Talking About Creatine

2,973

86%

61%

60%

“I love sports and enjoy going out with my friends to sporting events.”

consumers are familiar with creatine to enhance workouts

Awareness and usage do not go hand-in-hand

Creatine users workout preferences

Generally, Creatine users are more likely to participate in all workout related activities versus non users

Opportunity lies in discussing benefits of more regular use

Of the Creatine users, less than half are regular users

Most creatine users prefer to get their pre and post workout products via powdered beverage mixes

Most creatine users prefer to get their pre and post workout products via powdered beverage mixes

Consumers that currently use creatine tend to use other supplements as well

Product claims are more important to the creatine user than the general consumer

Creatine users trend higher than the general consumer in how they evaluate and respond to products

Blog

CREABEV™ versus standard creatine
monohydrate in ready-to-mix powdered
beverages

CREABEV™ shows positive
results for bioavailability

CREABEV™ shows similar sensory results
as compared to creatine monohydrate and
better than creatine HCL

Consumers Are
Talking About Creatine

consumers are familiar with creatine
to enhance workouts

Awareness and usage do not go
hand-in-hand

Opportunity lies in discussing
benefits of more regular use

Most creatine users prefer to get their pre
and post workout products via powdered
beverage mixes

Most creatine users prefer to get their pre
and post workout products via powdered
beverage mixes

Consumers that currently use creatine tend
to use other supplements as well

Product claims are more important to the
creatine user than the general consumer

Creatine users trend higher than the
general consumer in how they evaluate and
respond to products